Private liberal arts women's college in South Hadley, Massachusetts. It is the oldest member of the historic Seven Sisters colleges, a group of elite historically women's colleges in the Northeastern US.

Undergraduate admissions are restricted to female, transgender, and nonbinary students. In 2014, it became the first member of the Seven Sisters to introduce an admissions policy that was inclusive to transgender students.

However, all graduate programs are open to applicants regardless of gender. Unlike the open curriculums of the other liberal arts schools in the Five College Consortium, Mount Holyoke undergraduates are required to take at least one class each in the humanities, science or mathematics, social sciences, and foreign language, as well as a physical education requirement.

The college's 800-acre (3.2 km2) campus includes the Mount Holyoke College Art Museum, the John Payson Williston Observatory, and a botanic garden, and awards the Glascock Prize annually. Alumni and affiliates include notable poets, authors, feminists, academics, entertainers, scientists, politicians, and civil rights activists, as well as recipients of the Nobel Prize, Pulitzer Prize, Olympic Gold Medal, Rhodes Scholarship, Emmy Award, Golden Globe, and Academy Award.