The story of an Egyptian mage named Abraham, who taught a system of magic to Abraham of Worms.

Abraham of Worms passes his magical and Kabbalistic secrets on to his son and tells how he acquired his knowledge. Abraham recounts how he found Abramelin the Mage living in the desert outside an Egyptian town, Arachi or Araki, which borders the Nile. Abramelin's home sat atop a small hill surrounded by trees. He was an Egyptian mage and taught a powerful form of Kabbalistic magic to Abraham. He was a "venerable aged man", and very courteous and kind. He discussed nothing but "the Fear of God", the importance of leading a well-regulated life, and the evils of the "acquisition of riches and goods".

Abramelin extracted a promise from Abraham that he would give up his "false dogmas" and live "in the Way and Law of the Lord." He then gave Abraham two manuscript books to copy for himself, asking for ten gold florins, which he took with the intention of distributing to seventy-two poor persons in Arachi. Upon his return fifteen days later, after having disposed of the payment money, Abramelin extracted an oath from Abraham to "serve and fear" the Lord, and to "live and die in His most Holy Law." After this, Abramelin gave Abraham the "Divine Science" and "True Magic" embedded within the two manuscripts, which he was to follow and give to only those whom he knew well.

The system of magic from this book regained popularity in the 19th and 20th centuries partly due to Samuel Liddell MacGregor Mathers' translation, The Book of the Sacred Magic of Abramelin the Mage; and partly to its importance within the Hermetic Order of the Golden Dawn, and later within the mystical system of Thelema (created in 1904 by Aleister Crowley).

The book exists in the form of twelve manuscripts and an early printed edition. The provenance of the text has not been definitively identified. The earliest manuscripts are two versions that date from about 1608, are written in German and are now found in Wolfenbüttel. Another two manuscripts are in Dresden, and date from about 1700 and 1750 respectively.